September 28, 2014

MRSA Infection Treatment

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Decolonization of Methicillin-Resistant Staphylococcus aureus

MRSA kills more people each year than AIDS.  Children, elderly, sick and disabled who are non-verbal, are particularly vulnerable to MRSA infections. They can’t speak for themselves. They can’t tell you how sick they feel. They rely on caretakers to quickly identify staph infections. And seek prompt and effective medical treatment. 

Children have greater risk of MRSA infection in summer, while seniors have a greater risk in winter, according to a study published in American Journal of Epidemiology. My guess is children are more active in summer, attend camps, play more sports, thus getting more cuts that provide an open portal to Staphylococcus aureus, while many seniors are cooped up in nursing homes, aren’t being bathed and exposed to other immune compromised patients in winter.

Up to 20% of the US population is colonized with Staphylococcus aureus in anterior nares, with transient skin and nasal colonization rates as high as 60%. Staph aureus is a pathogenic opportunistic bacteria. In essence, it can be on your skin, but not until you get a burn, abrasion or cut, does it dive into the opening and spread its misery. If your doctor says you have a staph infection it is critical you:

·         *Ask doctor to perform a wound culture. As per culture results, demand appropriate antibiotic that is “susceptible” to the specific strain of Staphylococcus bacteria involved. 
       Getting the appropriate anti-biotic that targets specific strain of staph is the first line of defense in eradicating MRSA.

·         A wound culture can take up to 3 days. Few hospitals or healthcare providers have rapid detection MRSA tests. Troubling, considering an immune compromised or otherwise very ill person could die within few wait-for-wound-culture days, if they don’t get correct antibiotic.

·         *Ask doctor for prescription of MUPIROCIN. Normally, it’s applied to both nares twice a day x 5 days. (Studies show Mupirocin is more effective than Bacitracin in nasal decolonization of MRSA). 

·         *Ask doctor to prescribe CHLORHEXIDINE Gluconate mouthwash.

·         *Ask doctor to prescribe Hibiclens (CHLORHEXIDINE) for 5 days to do a full body wash (avoid eyes). You can find Hibiclens at your local pharmacy and at Walgreens, Wal Mart and Target.

·         If you are hospitalized with MRSA, or get MRSA while in the hospital (HA-MRSA) demand strict infection control protocol in place.

·        A study in Antimicrobial Resistance and Infection Control showed 21% of hospital nurses and 57% of surgical nurses are MRSA carriers. 

      A University of Michigan study showed 73% of nurses who wear artificial nails place patients at higher risk of MRSA via harmful bacteria on their nails. Deadly bacteria colonizes under artificial nails. Worse, artificial nails can tear apart latex gloves, spreading multi-drug resistant bacteria and blood to multiple patients. Doctor and nurse uniforms also transfer bacteria. (We had a nurse once that would work at a nursing home with very sick people, then go home and sleep, get up, and wear the same contaminated scrubs he wore to that job, to come work with our autistic son. Not good. No sense of infection control. No microbial thinking going on).  We have preventative measures in place at home because our autistic son attends an Autism Day Program. These types of programs are a hot bed of bacteria transmission. To prevent opportunistic bacteria, we give our autistic son two baths a day, and change his clothes frequently. We also use essential oils on his skin as a natural barrier to bacteria. 

·         Studies of MRSA decolonization show its role in reducing MRSA colonization and preventing reoccurring infections. Successful colonization is achieved if results are negative for MRSA in 3 consecutive follow-up culture tests.

                              NATURAL TREATMENTS TO ERADICATE MRSA

·         MANUKA HONEY: A study in the Journal of Antimicrobial Chemotherapy found that Manuka Honey contains anti-bacterial components. Researchers at the University of Wales College of Medicine found Manuka Honey destroyed MRSA inside leg ulcers.

·         EUCALYPTUS and TEA TREE OIL: According to a study in Reuter’s Health, a pair of surgeons turned researchers found that, applied to the skin of infected wounds, eucalyptus and tea tree oil can kill MRSA when conventional antibiotics fail, which means these essential oils can kill MRSA when antibiotics don’t fail, too, since antibiotic failure doesn’t alter therapeutic value of essential oils.

·         GARLIC: It can be used externally and internally to eradicate MRSA. A report in Nursing Times illuminated a study done at University of London, which showed garlic kills MRSA. It’s cheap and effective. Don’t count on the medical community to prescribe garlic anytime soon. The makers of bacitracin and mupirocin don’t appreciate competition from an herb you can find at your local farmer’s market or grocery store.

·         GOLDENSEAL: (H. canadensis). A study in Plana Medica shows the herb, Goldenseal is effective against MRSA.

·         NONPSYCHOACTIVE CANNABIOL: Aka, the medical cannabis that doesn’t get you “high”. According to a 2008, Science Daily report, substances in marijuana show potent germ killing activity against drug-resistant staphylococcus strains. 

       LAVENDER: Lavender oils inhibit growth of MSSA and MRSA, reported researchers in the Journal of Complementary Medicine

      LEMONGRASS for air disinfection: A study in Letter in Applied Microbiology found lemongrass disinfected the air by killing MRSA. If my autistic son was in hospital we would cover him with essential oils and diffuse the air around him. Don't count on air disinfection in hospitals. 

      MRSA is not the end of the world. There are effective antibiotics and natural treatments that can eradicate MRSA. Don't give up. 

Always consult your physician if you think you have a staph infection!

May 25, 2014

Caffeine May Save Brain Cells in People with Epilepsy

Might a cup of coffee a day help protect the brain from life-threatening seizure activity?

For many years the neuromodulator adenosine has been recognized as an endogenous anticonvulsant molecule and termed a “retaliatory metabolite.” As the core molecule of ATP, adenosine forms a unique link between cell energy and neuronal excitability.
Source:  Adenosine, Ketogenic Diet and Epilepsy: The Emerging Therapeutic Relationship Between Metabolism and Brain Activity

SUDEP is a serious problem that causes great fear among those who have epilepsy, especially in patients who are non verbal and can't tell us what they are experiencing. ..

 "Sudden unexpected death in epilepsy (SUDEP) is a significant cause of mortality in people with epilepsy. Two postulated causes for SUDEP, cardiac and respiratory depression, can both be explained by overstimulation of adenosine receptors. We hypothesized that SUDEP is a consequence of a surge in adenosine as a result of prolonged seizures combined with deficient adenosine clearance; consequently, blockade of adenosine receptors should prevent SUDEP. Here we induced impaired adenosine clearance in adult mice by pharmacologic inhibition of the adenosine-removing enzymes, adenosine kinase and deaminase. Combination of impaired adenosine clearance with kainic acid-induced seizures triggered sudden death in all animals. Most importantly, the adenosine receptor antagonist caffeine, when given after seizure onset, increased survival from 23.75 +/- 1.35 min to 54.86 +/- 6.59 min (p < 0.01).

 Our data indicate that SUDEP is due to overactivation of adenosine receptors and that caffeine treatment AFTER seizure onset might be beneficial."

Source:  2010 Mar;51(3):465-8. doi: 10.1111/j.1528-1167.2009.02248.x. Epub 2009 Aug 8.

A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance.